Ventricular Arrhythmias Symposium

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4th Annual International Symposium on Ventricular Arrhythmias: Pathophysiology and Therapy October 9-10, 2009 Loews Hotel Philadelphia, Philadelphia, PA

FRIDAY, OCTOBER 9, 2009
7:00 – 7:30 AM	Registration and Continental Breakfast
7:30-7:35 AM	Welcome Francis Marchlinski, MD Overview/Introduction David Callans, MD

Session 1 Basic Science Moderator: David Callans, MD
7:35 – 7:55 AM	Overview of stem cell biology, initial trials- Implications for VT Michael Rosen, MD
8:00 – 8:20 AM	Autonomic mechanisms and sudden death – basic science perspective Peng-Sheng Chen, MD
8:20 – 9:20 AM	10- Minute Presentations with Discussion: What themes in basic science will be important to clinical electrophysiologists in the next 5-10 years? Panel: Kevin Donahue,MD, Kalyanam Shivkumar,MD, PhD, Hiroshi Nakagawa , MD
9:20 – 9:40 AM	Coffee Break
Session 2 What discipline will provide the Rosetta Stone for sudden death risk assessment? Moderator: Francis Marchlinski, MD
9:40-10:00 AM	Epidemiology Douglas Zipes, MD
10:05-10:25 AM	Genetic Determinants Gordon Tomaselli, MD
10:30-10:50 AM	Clinical/Electrical Alfred Buxton, MD
10:55-11:15 AM	Imaging Timm Dickfeld, MD
11:20- 11:50 AM	Panel Discussion: Has our tendency to focus on risk of ventricular tachycardia distracted us from developing risk stratification strategies for sudden cardiac death? Eric Prystowsky, MD, Mark Josephson, MD, Melvin Scheinman, MD
12:00 PM -2:40 PM	Box Lunch and Live Cases
Live Cases (PENN EP Lab): Aortic cusp PVCs, Epicardial LV or RV Myopathy (Content preceded by short intro)
12:00–2:40 PM	Aortic cusp VT Moderator: David Callans, MD Panel: Andre d'Avila,MD, Samuel Asirvatham, MD Case Presentation: Fermin Garcia, MD, Mathew Hutchinson, MD Epicardial VT Moderator: Francis Marchlinski, MD Panel: Vivek Reddy, MD, Samuel Asirvatham, MD Case Presentation: Sanjay Dixit, MD, Edward Gerstenfeld, MD
Session 3 How can we improve device therapy? Moderator: Andre d’Avila, MD, PhD
2:40 – 3:00 PM	Why are ICD shocks associated with poor outcome? Jeanne Poole, MD
3:05 – 3:25 PM	What are the optimal device-based methods for minimizing ICD shocks? Kenneth Ellenbogen, MD
3:30 – 3:50 PM	CRT: Making it work and avoiding proarrhythmia? Michael Gold, MD, PhD
3:55 – 4:30 PM	Debate: Should device proarrhythmia and complications curb enthusiasm for primary prevention? Pro: Mark Josephson, MD Con: Eric Prystowsky, MD
4:30-4:45	Coffee Break
Session 4 Catheter ablation of idiopathic VT Moderator: Vivek Reddy, MD
4:45 – 5:05 PM	New anatomic /electrophysiologic correlates Sanjay Dixit, MD
5:10 – 5:30 PM	PVCs and tachycardia related myopathy Hans Kottkamp, MD
5:35 – 5:55 PM	Papillary muscle VTs Frank Bogun, MD
6:00 PM	Conference Adjourns

Saturday, October 10, 2009
7:00 – 7:30 AM	Registration and Continental Breakfast
7:30 AM	Morning Session Begins
Session 5 How can we improve treatment of patients with VT and structural heart disease? Moderator: Francis Marchlinski, MD
7:30 – 7:50 AM	Mortality following VT ablation William Stevenson, MD
7:55 – 8:15 AM	Does presentation with tolerated VT predict risk of sudden death? Andrew Epstein,MD
8:20 – 8:40 AM	Getting rid of antiarrhythmic drugs after ablation – Is it possible? Paolo Della Bella, MD
8:45 -9:15AM	Panel Discussion: Timing and follow-up of VT ablation: Optimizing results (from device programming to remodeling): Panel: Mark Estes, MD, Daniel Dries MD, MPH, David Haines, MD
9:15– 9:30 AM	Coffee Break
Session 6 Impact of epicardial mapping and ablation in non-ischemic VT Moderator: David Callans, MD
9:30 – 9:50 AM	Epicardial substrate in non-ischemic LV cardiomyopathy David Wilber, MD
9:55 – 10:15 AM	Epicardial substrate in ARVC/D Francis Marchlinski, MD
10:20 – 10:40 AM	Pathology of VT Substrate :Important considerations Jeffrey Saffitz, MD
10:45– 11:05 AM	Update on identification and prevention of complications Andre d’Avila, MD PhD
11:10 – 11:45 AM	Panel Discussion- Are we still underutilizing epicardial ablation? Speakers: Vivek Reddy, MD, Neal Kay,MD, William Stevenson, MD
11:45 – 12:45 PM	Lunch
12:45 PM	Afternoon Session Begins
Session 7 How can we better define the relationship between VT circuit and substrate? Moderator: David Callans, MD
12:45 – 1:00 PM	Insights from animal models Jacques de Bakker, MD, PhD
1:05 – 1:20 PM	Insights from electroanatomic mapping Christian de Chilliou, MD, PhD
1:25 –1:40 PM	Insights from resetting and entrainment mapping David Callans, MD
1:45 – 2:15 PM	Debate: We need more powerful ablation or mapping tools to be more successful in ablating VT Ablation tools: Vivek Reddy, MD Mapping: John Miller, MD
Session 8 VT Consensus Statement and Update on VT trials Moderator: Vivek Reddy, MD
2:20-2:35 PM	Lessons learned from the HRS/EHRA VT ablation consensus document William Stevenson, MD
2:35 – 2:50 PM	DETERMINE Kalyanam Shivkumar, MD, PhD
2:50 – 3:05 PM	CEASE VT Andrea Natale, MD
3:05 – 3:20 PM	MADIT CRT Arthur Moss, MD
3:20 – 3:45 PM	Panel Discussion: What questions should we study next? Hugh Calkins, MD, David Callans, MD, Mark Josephson, MD
3:45 – 4:00 PM	Coffee Break
Session 9 Challenges/New Directions Moderator: Francis Marchlinski, MD Critique/Discussion Panel: Paolo Della Bella, MD, Vivek Reddy, MD, Warren Jackman, MD, David Wilber, MD Each 10 Minute topic to be followed by a 10 minute critique and discussion.
4:00 – 4:10 PM	Dealing with epicardial vessels Andre d'Avila, MD, PhD
4:20 – 4:30 PM	Scar homogenization Pierre Jais, MD
4:40 – 4:50 PM	Automating the pacemap Edward Gerstenfeld, MD
5:00 – 5:10 PM	Moving beyond VT inducibility as an endpoint Francis Marchlinski, MD
5:20 – 5:30 PM	Penetrating scar/dealing with intramural scar Douglas Packer, MD
5:40 – 5:50 PM	What do we want from the ICD to aid in ablation therapy? Jesus Almendral, MD
6:00 PM	Conference Adjourns