Agenda 2025

SKIP THE LINES! | Thursday, October 9, 2025

3:30 – 6:30 PM Sign-In, Pick up your badge & handout early! | Salon G/H Foyer

Agenda - Friday, October 10, 2025

*All times are Eastern Daylight Time (EDT)

6:45 – 7:30 AM		Registration and Breakfast \| Please Visit Exhibits
7:15 – 7:30 AM		Virtual Attendees Sign-in to Online Platform
7:30 – 7:40 AM		Welcome and Introductions Francis Marchlinski, MD
		SESSION I Imaging in VT Ablation Moderator: Timm Dickfeld, MD, PhD Digital Moderator: Vivek Reddy, MD
7:40 – 7:50 AM		CT vs MRI for Deﬁnition of Scar Substrates and Emerging Role of Photon Counting CT Jeffrey Winterfield, MD
7:50 – 8:00 AM		Non-invasive Assessment of the Ventricular Arrhythmogenic Substrate: ECGi in Combination with CMR Ivo Roca-Luque, MD, PhD
8:00 – 8:10 AM		Near Field Analysis and ADAS Software to Localize Potential Ablation Sites Larry Chinitz, MD
8:10 – 8:20 AM		RCT – in EuroHeart – Study Results and Potential Implications Pierre Jaïs, MD
8:20 – 8:30 AM		Image Based Dissection of Ventricular Tachycardia Circuitry: Bridging the Gap Between Structure and Electrical Activity Saman Nazarian, MD, PhD
8:30 – 8:50 AM		Panel Discussion with Q&A Session
		SESSION II Device Therapy in VT/VF Management *Moderator:* Paul Wang, MD Digital Moderator: Devi Nair, MD
8:50 – 9:00 AM		Device Prevention of SCD: Where Are We in 2025 Jeanne Poole, MD
9:00 – 9:10 AM		New Systems for Treating VT Without Intravascular Leads Michael Gold, MD, PhD
9:10 – 9:20 AM		Clinical Value in Visualization of the Conduction System for CRT Kenneth Ellenbogen, MD
9:20 – 9:30 AM		Left Bundle Pacing and Optimized CRT with Novel ICD Leads Pugazhendhi Vijayaraman, MD
9:30 – 9:40 AM		Can Quantitative Vector Screening for SubQ ICD Reduce Inappropriate Shocks? David Frankel, MD
9:40 – 10:00 AM		EP Heavyweight Debate CRT-P versus CRT-D for NICM Patients with LV Dysfunction and LBBB • CRT-P: Robert Schaller, DO • CRT-D: Peter Zimetbaum, MD
10:00 – 10:20 AM		Panel Discussion with Q&A Session Including discussion of advanced heart failure treatment and CCM
10:20 – 10:40 AM		Coffee Break \| Visit Exhibits
		SESSION III Ventricular Fibrillation *Moderator:* Francis Marchlinski, MD Digital Moderator: Magdi Saba, MD
10:40 – 10:50 AM		AI Assisted ECG as a Risk Prediction Tool for VF Samuel Asirvatham, MD
10:50 – 11:00 AM		Updates on the His-Purkinje System in VF John Miller, MD
11:00 – 11:10 AM		Multicenter Study of Idiopathic VF: Detection of Etiological Diagnosis (hidden diseases) by Long Term Monitoring Michel Haïssaguerre, MD, PhD
11:10 – 11:20 AM		Distinguishing Pseudo Torsades de Pointes from True Torsades de Pointes Samuel Viskin, MD
11:20 – 11:30 AM		Prerecorded Case of VF Ablation – Bordeaux Strategy Mélèze Hocini, MD, PhD
11:30 – 11:40 AM		Bravo Study and Brugada Syndrome: Clinical Implications Koonlawee Nadamanee, MD
11:40 AM – 12:00 PM		Panel Discussion with Q&A Session
12:00 – 12:05 PM		Pick up Box Lunch
		SESSION IV Live Cases (Working Lunch) *Moderator: Francis Marchlinski, MD Digital Moderator:* Luigi Di Biase, MD, PhD *Panel:* Wendy Tzou, MD, Roderick Tung, MD, Miguel Valderrábano, MD, PhD, Pasquale Santangeli, MD, PhD, William Stevenson, MD, Pierre Jaïs, MD, Thomas Deneke, MD Hospital of University of Pennsylvania, Philadelphia, PA Operators/Onsite discussants: Fermin Garcia, MD, Andres Enriquez, MD, David Lin MD Gregory Supple, MD, Robert Schaller, DO, Sanjay Dixit MD Matthew Hyman, MD, PhD, Timothy Markman MD, Ramanan Kumareswaran, MD
		SESSION V Mechanistic Considerations *Moderator:* David Callans, MD Digital Moderator: Mohit Turagam, MD
1:50 – 2:00 PM		How Connexin and Ion Channel Alterations Combine to Build the Functional Part of the VT Substrate J. Kevin Donahue, MD
2:00 – 2:10 PM		How Gene Therapy Amends the Electrophysiologic Substrate Silvia Priori, MD, PhD
2:10 – 2:20 PM		Detailed Substrate Distribution and Outcome after Catheter Ablation in Gene Positive and Gene Elusive Patients with NICM Katja Zeppenfeld, MD, PhD
2:20 – 2:30 PM		Overcoming the Arrhythmia Management Challenges Posed by Myocardial Inﬂammation William Sauer, MD
2:30 – 240 PM		Desmosomal Ultrastructure to Identify Novel Molecular Targets for VT Ablation Giovanni Peretto, MD, PhD
2:40 – 3:00 PM		Panel Discussion with Q&A Session
3:00 – 3:20 PM		Coffee Break \| Visit Exhibits
		SESSION VI Late Breaking + New/Ongoing Trial Results/Information *Moderator:* Vivek Reddy, MD *Digital Moderator:* David Callans, MD
3:20 – 3:30 PM		Results from the LESS VT Study in NICM Paolo Della Bella, MD
3:30 – 3:40 PM		Brazilian BiV versus CSP RCT Andre d’Avila, MD, PhD
3:40 – 3:50 PM		VT Symposium LBCT Competition/TBD TBD
3:50 – 4:00 PM		VT Symposium LBCT Competition/TBD TBD
4:00 – 4:20 PM		Panel Discussion
		New/Ongoing Trials – Rapid Fire Presentations
4:20 – 4:27 PM		Radiate VT Update Phillip Cuculich, MD
4:27 – 4:34 PM		FACILE VT Roderick Tung, MD
4:34 – 4:41 PM		EASY-R: Outcomes with a Novel Pericardial Access Tool Petr Neuzil MD, PhD
4:41 – 4:48 PM		Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT Douglas Packer, MD
4:48 – 4:55 PM		Words of Advice – Are we Heading in the Right Direction? David Callans, MD
		SESSION VII New Diagnostic/Therapeutic Criteria/ Techniques/Strategies *Moderator:* Andre d’Avila, MD, PhD *Digital Moderator:* Vivek Reddy, MD
4:55 – 5:05 PM		The Misleading QRS: Discrepancies Between VT Morphology and Site of Origin William Stevenson, MD
5:05 – 5:15 PM		ARVC VT: Endo Ablation-Who Beneﬁts? Targeting ICE deﬁned RV Aneurysms for Better Outcome Francis Marchlinski, MD
5:15 – 5:25 PM		Progress in Mapping Fixed Versus Functional Block in VT Substrate Ablation Timothy Maher, MD
5:25 – 5:35 PM		Cardiogenetic Disease: Role of the Immune System Carlo Pappone, MD, PhD
5:35 – 5:45 PM		Pacemapping for VT Ablation: New Insights Christian de Chillou, MD, PhD
5:45 – 5:55 PM		Presence of Mid-Myocardial Fibrosis in Ventricular Endocardial Electrograms is Related to Power of Patient-Speciﬁc Frequency Bands Usha Tedrow, MD, MS
5:55 – 6:05 PM		PFA for Bailout VT Ablation in USA – Early Clinical Experience + Some Challenges to Overcome Pasquale Santangeli, MD, PhD
6:05 – 6:25 PM		Panel Discussion with Q&A Session
6:25 – 6:30 PM		Day 1 Wrap up Francis Marchlinski, MD
6:30 – 7:30 PM		Welcome Reception Best Abstract Finalist Posters and Highlights from Late Breaking Trial Results

Agenda - Saturday, October 11, 2025

*All times are Eastern Daylight Time (EDT)

6:45 – 7:30 AM		Registration and Breakfast \| Please Visit Exhibits
7:15 – 7:25 AM		Virtual Attendees Sign-in to Online Platform
7:25 – 7:30 AM		Welcome Day 2 David Callans, MD
		SESSION VIII Risk Assessment for Ventricular Arrhythmias *Moderator:* Mina Chung, MD *Digital Moderator:* Tarv Dhanjal, PhD, FRCP
7:30 – 7:40 AM		SCD: The Latest Clinical Trials and PROFID Update Gerhard Hindricks, MD
7:40 – 7:50 AM		Ring-Like Arrhythmogenic Cardiomyopathy: New insights into Genetics, Risk Stratiﬁcation and Management Daniele Muser, MD, PhD
7:50 – 8:00 AM		Enhancing Arrhythmia Risk Prediction in NICM through Multi-modal AI Natalia Trayanova, PhD, MS
8:00 – 8:10 AM		Update on Risk Assessment for Malignant MVP Syndrome Marc Miller, MD
8:10 – 8:20 AM		NSVT: Reevaluating its Impact and Signiﬁcance on Sudden Cardiac Death Risk Assessment Rajat Deo, MD
8:20 – 8:30 AM		ECG/Mapping as Risk Prediction Tools for Ventricular Arrhythmias with AI - Moving from Theory to Implementation Kalyanam Shivkumar, MD, PhD
8:30 – 8:50 AM		Panel Discussion with Q&A Session
		SESSION IX Developing VT Ablation Strategies *Moderator:* Wendy Tzou, MD *Digital Moderator:* Usha Tedrow, MD, MS
8:50 – 9:00 AM		Maximizing Ablation Lesion Size with Prolonged Duration PFA: Insights from Pre-clinical and Clinical Studies Cory Tschabrunn, PhD
9:00 – 9:10 AM		Prerecorded Case of Affera VT Ablation Josef Kautzner, MD, PhD
9:10 – 9:20 AM		Identifying VT Circuit Characteristics by High Density Mapping and Altering Wavefronts Roderick Tung, MD
9:20 – 9:30 AM		Focal PFA for PVC Ablation (Farapoint focal catheter) Srinivas Dukkipati, MD
9:30 – 9:40 AM		High Voltage PFA for VT: Insights from Porcine Model of Chronic Infarction Cory Tschabrunn, PhD
9:40 – 10:00 AM		Panel Discussion with Q&A Session
10:00 – 10:20 AM		Coffee Break \| Visit Exhibits
		SESSION X Annual Mark E. Josephson Memorial Lecture *Moderator:* Francis Marchlinski, MD *Panel:* Vivek Reddy, MD, David Callans, MD, Kalyanam Shivkumar, MD, PhD, Roderick Tung, MD, Karl-Heinz Kuck, MD
10:20 – 10:25 AM		Introduction of Dr. Della Bella by Dr. Marchlinski
10:25 – 10:45 AM		VT Recurrence after Ablation: How Can We Fight, How Wise Should We Behave? Paolo Della Bella, MD
10:45 – 11:00 AM		Panel Discussion with Q&A Session
		SESSION XI Non-ablative Treatments for Ventricular Arrhythmias *Moderator:* Karl-Heinz Kuck, MD *Digital Moderator:* Jackson Liang, DO
11:00 – 11:10 AM		DEBATE: Early VT/VF Ablation: Hope or Hype? Kalyanam Shivkumar, MD, PhD
11:10 – 11:20 AM		Surgical Autonomic Denervation as Treatment for Multifocal PVCs: Multicenter Registry Krishna Pothineni, MD
11:20 – 11:30 AM		Do AADs Decrease Recurrence After VT Ablation? Jesus Almendral, MD, PhD
11:30 – 11:40 AM		Cardiac Sympathetic Denervation for VT/VF – Updates for 2025 Olujimi Ajijola, MD, PhD
11:40 – 11:50 AM		Autonomic Modulation in the EP Lab: Stellate Ganglion Miguel Valderrábano, MD, PhD
11:50 AM – 12:00 PM		VANISH2: Outcomes by Antiarrhythmic Drug Assignment John Sapp MD
12:00 – 12:25 PM		Panel Discussion with Q&A Session
12:25 – 12:35 PM		Pick up Box Lunch
		SESSION XII Pre-Recorded Live Cases (Working Lunch) (15 minutes and 5 minute Q&A) *Moderator:* Roderick Tung, MD *Digital Moderator:* Gregory Supple, MD Panel: Usha Tedrow, MD, MS, Sanjay Dixit, MD, Karl-Heinz Kuck, MD, Andres Enriquez, MD, Ivo Roca-Luque, MD, PhD, Srinivas Dukkipati, MD
12:35 – 1:55 PM		Farapoint PVC Ablation: Mt Sinai Daniel Musikantow, MD / TBD MD WADL Ablation in Real Time: Beth Israel Andre d’Avila, MD, PhD / Timothy Maher, MD Image Guided High Voltage VT Ablation: Mt. Sinai Vivek Reddy, MD / TBD, MD Epicardial Access via RAA: Cleveland Clinic Pasquale Santangeli, MD, PhD / Koji Higuchi, MD
		SESSION XIII Mark E. Josephson Abstract Competition & VT Innovation Award *Moderator:* David Callans, MD *Panel:* Vivek Reddy, MD, Francis Marchlinski, MD, Srinivas Dukkipati, MD, Andre d’Avila, MD, PhD
1:55 PM		Introduction David Callans, MD
		Abstract Presentations from the 2 Finalists
1:57 – 2:09 PM		Presentation 1
2:09 – 2:21 PM		Presentation 2
2:21 – 2:25 PM		Judges Review and VT Innovation Award Presented for the Best Abstract
2:25 – 2:45 PM		Break \| Visit Exhibits
		SESSION XIV VT Potpourri *Moderator:* William Whang, MD *Digital Moderator:* Matthew Hyman, MD, PhD
2:45 – 2:55 PM		Relevance of Inﬂammation to VT/PVCs in Early and Late-Stage Cardiomyopathy Jason Bradfield, MD
2:55 – 3:05 PM		Early Versus Late VT Recurrence in NICM Andrea Natale, MD
3:05 – 3:15 PM		Ultracool Cryoablation for VT: Initial Experience Gregory Supple, MD
3:15 – 3:25 PM		Can Tissue Impedance Distinguish Sarcoid from Non-inﬂammatory CM? Wendy Tzou, MD
3:25 – 3:40 PM		Panel Discussion with Q&A Session
		SESSION XV PVCs *Moderator:* David Frankel, MD *Digital Moderator:* Stavros Mountantonakis, MD, MBA
3:40 – 3:50 PM		Stepwise Approach to Intramural Outﬂow Tract PVCs Fermin Garcia, MD
3:50 – 4:00 PM		Ablation of PVCs from the GCV/AIV-Papillary Muscles with PFA Josef Kautzner, MD, PhD
4:00 – 4:10 PM		Vertebral Vein Stimulation for PVC Induction Timothy Markman, MD
4:10 – 4:20 PM		Watchful Waiting for Frequent Asymptomatic PVCs Frank Bogun, MD
4:20 – 4:35 PM		Panel Discussion with Q&A Session
		SESSION XVI Pulsed Field Ablation of VT *Moderator:* Srinivas Dukkipati, MD *Digital Moderator:* Francis Marchlinski, MD
4:35 – 4:45 PM		The Promise of PFA for VT Ablation: Is it Really a Game Changer? Elad Anter, MD
4:45 – 4:55 PM		Prediction of Durable PFA Lesion Size in the Normal and Scarred Ventricular Myocardium Hiroshi Nakagawa, MD, PhD
4:55 – 5:05 PM		Updates: PFA and the Ventricular Substrate Jacob Koruth, MD
5:05 – 5:15 PM		Pulse Field Ultra-Low Temperature Cryoablation: Lesion Creation and Effect on Coronary Arteries in a Swine Model Edward Gerstenfeld, MD
5:15 – 5:25 PM		Prerecorded Case - Combined RF and PF for VT Ablation Atul Verma, MD
5:25 – 5:35 PM		Real Time Feedback During PFA in the Ventricle Harikrishna Tandri, MD
5:35 – 5:55 PM		Panel Discussion with Q&A Session
5:55 – 6:00 PM		Closing Comments and Invitation to VT Symposium 2026 Francis Marchlinski, MD

Faculty

20^th Annual International Symposium on Ventricular Arrhythmias

Course Directors

Francis Marchlinski, MD University of Pennsylvania Health System Philadelphia, PA		Andre d’Avila, MD, PhD Beth Israel Deaconess Medical Center, Boston, MA
David Callans, MD University of Pennsylvania Health System Philadelphia, PA		Srinivas Dukkipati, MD The Mount Sinai Hospital New York, NY
Vivek Reddy, MD The Mount Sinai Hospital New York, NY

Faculty

Olujimi Ajijola, MD, PhD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA

Jesus Almendral, MD, PhD
Hospital de Madrid Group
Madrid, Spain

Elad Anter, MD
Shamir Medical Center University of Tel Aviv
Tel Aviv, Israel

Samuel Asirvatham, MD
Mayo Clinic
Rochester, MN

Frank Bogun, MD
University of Michigan Health System
Ann Arbor, MI

Jason Bradfield, MD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA

Larry Chinitz, MD
NYU Langone Health
New York, NY

Mina Chung, MD
Cleveland Clinic
Cleveland, OH

Phillip Cuculich, MD
Washington University School of Medicine
St. Louis, MO

Christian de Chillou, MD, PhD
University Hospital Nancy
Nancy, France

Paolo Della Bella, MD
IRCCS San Raffaele Scientific Institute
Milan, Italy

Thomas Deneke, MD
University Heart Center
Paracelsus Medical University
Nuremberg, Germany

Rajat Deo, MD
University of Pennsylvania Health System
Philadelphia, PA

Tarv Dhanjal, PhD, FRCP
Warwick Medical School
University of Warwick
Coventry, UK

Luigi Di Biase, MD, PhD
Albert Einstein College of Medicine at Montefiore Hospital
Bronx, NY

Timm Dickfeld, MD, PhD
University of Maryland Medical Center
Baltimore, MD

Sanjay Dixit, MD
University of Pennsylvania Health System
Philadelphia, PA

J. Kevin Donahue, MD
UMass Chan Medical School
Worchester, MA

Kenneth Ellenbogen, MD
VCU Health
Richmond, VA

Andres Enriquez, MD
University of Pennsylvania Health System
Philadelphia, PA

David Frankel, MD
University of Pennsylvania Health System
Philadelphia, PA

Fermin Garcia, MD
University of Pennsylvania Health System
Philadelphia, PA

Edward Gerstenfeld, MD, MS
University of California San Francisco
San Francisco, CA

Michael Gold, MD, PhD
Medical University of South Carolina
Charleston, SC

Michel Haïssaguerre, MD, PhD
Bordeaux University Hospital
Bordeaux, France

Koji Higuchi, MD
Cleveland Clinic
Cleveland, OH

Gerard Hindricks, MD
Charité-University of Berlin
Berlin, Germany

Mélèze Hocini, MD
Bordeaux University Hospital
Bordeaux, France

Matthew Hyman, MD, PhD
University of Pennsylvania Health System
Philadelphia, PA

Pierre Jaïs, MD
Bordeaux University Hospital
Bordeaux, France

Josef Kautzner, MD, PhD
Institute for Clinical and Experimental Medicine (IKEM)
Prague, Czech Republic

Jacob Koruth, MD
The Mount Sinai Hospital
New York, NY

Karl-Heinz Kuck, MD
LANS Cardio
Hamburg, Germany

Ramanan Kumareswaran, MD
University of Pennsylvania Health System
Philadelphia, PA

Jackson Liang, DO
University of Michigan Health System
Ann Arbor, MI

David Lin, MD
University of Pennsylvania Health System
Philadelphia, PA

Timothy Maher, MD
Beth Israel Deaconess Medical Center
Boston, MA

Timothy Markman, MD
University of Pennsylvania Health System
Philadelphia, PA

Stavros Mountantonakis, MD, MBA
Lennox Hill Hospital, Northwell Health
New York, NY

John Miller, MD
Indiana University School of Medicine
Indianapolis, IN

Marc Miller, MD
The Mount Sinai Hospital
New York, NY

Daniele Muser, MD, PhD
Humanitas University
Milan, Italy

Daniel Musikantow, MD
The Mount Sinai Hospital
New York, NY

Koonlawee Nadamanee, MD
Center of Excellence in Arrhythmia Research
Chulalongkorn University
Bangkok, Thailand

Devi Nair, MD
St. Bernard's Heart & Vascular
Center & Arrhythmia Research Group
Jonesboro, AR

Hiroshi Nakagawa, MD, PhD
Cleveland Clinic Cleveland, OH

Andrea Natale, MD
Texas Cardiac Arrhythmia Institute
Austin, TX

Saman Nazarian, MD, PhD
University of Pennsylvania Health System
Philadelphia, PA

Petr Neuzil, MD, PhD
Na Homolce Hospital Prague
Czech Republic

Douglas Packer, MD
Intermountain Medical Center
Murray, UT

Carlo Pappone, MD, PhD
IRCCS Policlinico Dan Donato
Milan, Italy

Giovanni Peretto, MD, PhD
IRCCS San Raffaele Scientific Institute
Milan, Italy

Jeanne Poole, MD
University of Washington
Seattle, WA

Krishna Pothineni, MD
Kansas City Heart Rhythm Institute
Kansas City, MO

Silvia Priori, MD, PhD
University of Pavia
Pavia, Italy

Ivo Roca-Luque, MD, PhD
University of Barcelona – Institut Clinic Cardiovascular
Barcelona, Spain

Magdi Saba, MD
St. George's University Hospital
London, England

Pasquale Santangeli, MD, PhD
Cleveland Clinic
Cleveland, OH

John Sapp, MD
QEII Health Sciences Center
Halifax, NS, Canada

William Sauer, MD
Brigham and Women’s Hospital
Boston, MA

Robert Schaller, DO
University of Pennsylvania Health System
Philadelphia, PA

Kalyanam Shivkumar, MD, PhD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA

William Stevenson, MD
Vanderbilt University School of Medicine
Nashville, TN

Gregory Supple, MD
University of Pennsylvania Health System
Philadelphia, PA

Harikrishna Tandri, MBBS, MD
Vanderbilt University Medical Center
Nashville, TN

Usha Tedrow, MD, MS
Brigham and Women’s Hospital
Boston, MA

Natalia Trayanova, PhD, MS
Johns Hopkins University
Baltimore, MD

Cory Tschabrunn, PhD
University of Pennsylvania Health System
Philadelphia, PA

Roderick Tung, MD
The University of Arizona College of Medicine – Phoenix
Phoenix, AZ

Mohit Turagam, MD
The Mount Sinai Hospital
New York, NY

Wendy Tzou, MD
University of Colorado
School of Medicine
Anschutz Medical Campus
Aurora, CO

Miguel Valderrábano, MD, PhD
Houston Methodist Debakey Cardiology
Houston, TX

Atul Verma, MD
McGill University Health Center
Montreal, Qubec, Canada

Pugazhendhi Vijayaraman, MD
Geisinger-Wyoming Valley Medical Center
Wilkes-Barre, PA

Samuel Viskin, MD
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel

Paul Wang, MD
Stanford University
Stanford, CA

William Whang, MD
The Mount Sinai Hospital
New York, NY

Jeffrey Winterfield, MD
Medical University of South Carolina
Charleston, SC

Katja Zeppenfeld, MD, PhD
University of Leiden
Leiden, Netherlands

Peter Zimetbaum, MD
Beth Israel Deaconess Medical Center
Boston, MA

Industry Partners

Partners In Educational Advancements In Ventricular Arrhythmia Management

The University of Pennsylvania Health System and The Mount Sinai Hospital serve as the host and sponsoring institutions for the VT Symposium, which is partly funded through educational grants and sponsorships from our industry partners.

This conference is made possible in part by the support of our industry colleagues, who are dedicated to educating healthcare professionals and improving patient outcomes.

Recognition of Educational Grantors will be announced shortly.

Recognition of Exhibitors will be announced shortly.

For information about support opportunities, please contact us:

SUPPORT OPPORTUNITES >>