Welcome and Introductions
Francis Marchlinski, MD

SESSION I
Imaging in VT Ablation
Moderator: Timm Dickfeld, MD, PhD
Digital Moderator: Vivek Reddy, MD

CT vs MRI for Definition of Scar Substrates and Emerging Role of Photon Counting CT
Jeffrey Winterfield, MD

Non-invasive Assessment of the Ventricular Arrhythmogenic Substrate: ECGi in Combination with CMR
Ivo Roca-Luque, MD, PhD

Near Field Analysis and ADAS Software to Localize Potential Ablation Sites
Larry Chinitz, MD

Image Based Dissection of Ventricular Tachycardia Circuitry: Bridging the Gap Between Structure and Electrical Activity
Saman Nazarian, MD, PhD

Panel Discussion with Q&A Session

RCT – in EuroHeart – Study Results and Potential Implications
This presentation, originally scheduled for Session I, occurred as a special evening presentation on Day 1.
Pierre Jaïs, MD

SESSION II 
Device Therapy in VT/VF Management
Moderator: Paul Wang, MD
Digital Moderator: Devi Nair, MD

Device Prevention of SCD: Where Are We in 2025
Paul Wang, MD

New ICD Systems for Treating VT Without Intravascular Leads
Michael Gold, MD, PhD

Clinical Value in Visualization of the Conduction System for CRT
Kenneth Ellenbogen, MD

Left Bundle Pacing and Optimized CRT with Novel ICD Leads
Pugazhendhi Vijayaraman, MD

Can Quantitative Vector Screening for SubQ ICD Reduce Inappropriate Shocks?
David Frankel, MD

EP Heavyweight Debate
CRT-P versus CRT-D for NICM Patients with LV Dysfunction and LBBB
• CRT-P: Robert Schaller, DO
• CRT-D: Peter Zimetbaum, MD

Panel Discussion with Q&A Session
Including discussion of advanced heart failure treatment and CCM

SESSION III
Ventricular Fibrillation
Moderator: Francis Marchlinski, MD
Digital Moderator: Magdi Saba, MD

AI Assisted ECG as a Risk Prediction Tool for VF
Samuel Asirvatham, MD

Updates on the His-Purkinje System in VF
John Miller, MD

Multicenter Study of Idiopathic VF: Detection of Etiological Diagnosis (hidden diseases) by Long Term Monitoring
Michel Haïssaguerre, MD, PhD

Distinguishing Pseudo Torsades de Pointes from True Torsades de Pointes
Samuel Viskin, MD

Prerecorded Case of VF Ablation – Bordeaux Strategy
Mélèze Hocini, MD, PhD

BRAVE Study and Brugada Syndrome: Clinical Implications
Koonlawee Nadamanee, MD

Panel Discussion with Q&A Session

SESSION IV 
Live Cases
Moderator: Francis Marchlinski, MD
Digital Moderator: Luigi Di Biase, MD, PhD
Panel: Wendy Tzou, MD, Roderick Tung, MD, Miguel Valderrábano, MD, PhD, Pasquale Santangeli, MD, PhD, William Stevenson, MD, Pierre Jaïs, MD, Thomas Deneke, MD

Hospital of University of Pennsylvania, Philadelphia, PA Operators/Onsite discussants:

• Fermin Garcia, MD, Andres Enriquez, MD, David Lin MD
• Gregory Supple, MD, Robert Schaller, DO, Sanjay Dixit MD
• Matthew Hyman, MD, PhD, Timothy Markman MD, Ramanan Kumareswaran, MD

SESSION V
Mechanistic Considerations
Moderator: David Callans, MD
Digital Moderator: Mohit Turagam, MD

How Connexin and Ion Channel Alterations Combine to Build the Functional Part of the VT Substrate
J. Kevin Donahue, MD

Detailed Substrate Distribution and Outcome after Catheter Ablation in Gene Positive and Gene Elusive Patients with NICM
Katja Zeppenfeld, MD, PhD

Overcoming the Arrhythmia Management Challenges Posed by Myocardial Inflammation
William Sauer, MD

Desmosomal Ultrastructure to Identify Novel Molecular Targets for VT Ablation
Giovanni Peretto, MD, PhD

Panel Discussion with Q&A Session

SESSION VI
Late Breaking + New/Ongoing Trial Results/Information
Moderator: David Callans, MD
Digital Moderator: Luigi Di Biase, MD, PhD

Results from the LESS VT Study in NICM
Paolo Della Bella, MD

Brazilian BiV versus CSP RCT
Andre d’Avila, MD, PhD

A Dual-Energy Lattice-Tip Focal Catheter for Mapping and Ablation to Treat Ventricular Tachycardia: Acute Outcomes of the Sphere-9 VT Early Feasibility Study
Vivek Reddy, MD

Ultralow Temperature Cryoablation of Ventricular Tachycardia: Interim Analysis of Acute Outcomes of the FULCRUM-VT Trial
Travis Richardson, MD

High-Voltage Focal Pulsed Field Ablation to Treat Scar-Related Ventricular Tachycardia: Final 6-Month Outcomes of the First-in-Human VCAS Trial
Vivek Reddy, MD

Panel Discussion

New/Ongoing Trials – Rapid Fire Presentations

Radiate VT Update
Phillip Cuculich, MD

SESSION VII
New Diagnostic/Therapeutic Criteria/ Techniques/Strategies
Moderator: Andre d’Avila, MD, PhD  
Digital Moderator: Vivek Reddy, MD

The Misleading QRS: Discrepancies Between VT Morphology and Site of Origin
William Stevenson, MD

ARVC VT Endo Only Ablation: Who Benefits/Targeting ICE Defined Aneurysms for Better Outcome
Francis Marchlinski, MD

Progress in Mapping Fixed Versus Functional Block in VT Substrate Ablation
Timothy Maher, MD

Cardiogenetic Disease: Role of the Immune System
Carlo Pappone, MD, PhD

Pacemapping for VT Ablation: New Insights
Christian de Chillou, MD, PhD

Presence of Mid-Myocardial Fibrosis in Ventricular Endocardial Electrograms is Related to Power of Patient-Specific Frequency Bands
Usha Tedrow, MD, MS

PFA for Bailout VT Ablation in USA – Early Clinical Experience + Some Challenges to Overcome
Pasquale Santangeli, MD, PhD

Panel Discussion with Q&A Session

SESSION VIII
Risk Assessment for Ventricular Arrhythmias
Moderator: Mina Chung, MD 
Digital Moderator: Tarv Dhanjal, PhD, FRCP

SCD: The Latest Clinical Trials and PROFID Update
Gerhard Hindricks, MD

Ring-Like Arrhythmogenic Cardiomyopathy: New insights into Genetics, Risk Stratification and Management
Daniele Muser, MD, PhD

Enhancing Arrhythmia Risk Prediction in NICM through Multi-modal AI
Natalia Trayanova, PhD, MS

Update on Risk Assessment for Malignant MVP Syndrome
Marc Miller, MD

NSVT: Reevaluating its Impact and Significance on Sudden Cardiac Death Risk Assessment
Rajat Deo, MD

ECG/Mapping as Risk Prediction Tools for Ventricular Arrhythmias with AI - Moving from Theory to Implementation
Kalyanam Shivkumar, MD, PhD

Panel Discussion with Q&A Session

SESSION IX
Developing VT Ablation Strategies
Moderator: Wendy Tzou, MD
Digital Moderator: Usha Tedrow, MD, MS

Maximizing Ablation Lesion Size with Prolonged Duration PFA: Insights from Pre-clinical and Clinical Studies
Cory Tschabrunn, PhD

Prerecorded Case of VT Ablation Using a Large Footprint Lattice Tip Catheter
Josef Kautzner, MD, PhD

Identifying VT Circuit Characteristics by High Density Mapping and Altering Wavefronts
Roderick Tung, MD

Focal PFA for PVC Ablation
Srinivas Dukkipati, MD

High Voltage PFA for VT: Insights from Porcine Model of Chronic Infarction
Cory Tschabrunn, PhD

Panel Discussion with Q&A Session

SESSION X
Annual Mark E. Josephson Memorial Lecture
Moderator: Francis Marchlinski, MD
Panel: Vivek Reddy, MD, David Callans, MD, Kalyanam Shivkumar, MD, PhD, Roderick Tung, MD, Karl-Heinz Kuck, MD

Introduction of Dr. Della Bella by Dr. Marchlinski

VT Recurrence after Ablation: How Can We Fight, How Wise Should We Behave?
Paolo Della Bella, MD

Panel Discussion with Q&A Session

SESSION XI
Non-ablative Treatments for Ventricular Arrhythmias
Moderator: Karl-Heinz Kuck, MD
Digital Moderator: Jackson Liang, DO

Automatic Nervous System and Ventricular Arrhythmias
Kalyanam Shivkumar, MD, PhD

Surgical Autonomic Denervation as Treatment for Multifocal PVCs: Multicenter Registry
Krishna Pothineni, MD

Do AADs Decrease Recurrence After VT Ablation?
Jesus Almendral, MD, PhD

Cardiac Sympathetic Denervation for VT/VF – Updates for 2025
Olujimi Ajijola, MD, PhD

Autonomic Modulation in the EP Lab: Stellate Ganglion Recording and Stimulation
Miguel Valderrábano, MD, PhD

VANISH2: Outcomes by Antiarrhythmic Drug Assignment
John Sapp MD

Panel Discussion with Q&A Session

SESSION XII
Pre-Recorded Live Cases (Working Lunch) (15 minutes and 5 minute Q&A)
Moderator: Roderick Tung, MD
Digital Moderator: Gregory Supple, MD Panel: Usha Tedrow, MD, MS, Sanjay Dixit, MD, Karl-Heinz Kuck, MD, Andres Enriquez, MD, Ivo Roca-Luque, MD, PhD, Srinivas Dukkipati, MD

1. PVC Ablation Using Focal-Linear PFA Catheter: Mount Sinai
   Daniel Musikantow, MD / TBD MD
2. WADL Ablation in Real Time: Beth Israel
   Andre d’Avila, MD, PhD / Timothy Maher, MD
3. Image Guided High Voltage VT Ablation: Mt. Sinai
   Vivek Reddy, MD / TBD, MD
4. Epicardial Access via RAA: Cleveland Clinic
   Pasquale Santangeli, MD, PhD / Koji Higuchi, MD

SESSION XIII
Mark E. Josephson Abstract Competition & VT Innovation Award
Moderator: David Callans, MD
Panel: Vivek Reddy, MD, Francis Marchlinski, MD, Srinivas Dukkipati, MD, Andre d’Avila, MD, PhD

Introduction
David Callans, MD

Abstract Presentations from the 2 Finalists

Utilizing Stored Implanted Cardiac Electrograms to Target Fascicular Substrate in Catheter Ablation of Ventricular Fibrillation
Robert Kerley, MD

High-intensity ultrasound catheter ablation for deep mid-myocardial substrates: optimization for transmural lesions through contact sensing
Craig C Morris, MD

Judges Review and VT Innovation Award Presented for the Best Abstract

SESSION XIV
VT Potpourri
Moderator: William Whang, MD
Digital Moderator: Matthew Hyman, MD, PhD

Relevance of Inflammation to VT/PVCs in Early and Late-Stage Cardiomyopathy
Jason Bradfield, MD

Early Versus Late VT Recurrence in NICM
Luigi Di Biase, MD, PhD

Ultracool Cryoablation for VT: Initial Experience
Gregory Supple, MD 

Can Tissue Impedance Distinguish Sarcoid from Non-inflammatory CM?
Wendy Tzou, MD

Panel Discussion with Q&A Session

SESSION XV
PVCs
Moderator: David Frankel, MD
Digital Moderator: Stavros Mountantonakis, MD, MBA

Stepwise Approach to Intramural Outflow Tract PVCs
Fermin Garcia, MD

Ablation of PVCs from the GCV/AIV-Papillary Muscles with PFA
Josef Kautzner, MD, PhD

Vertebral Vein Stimulation for PVC Induction
Timothy Markman, MD

Watchful Waiting for Frequent Asymptomatic PVCs
Frank Bogun, MD

Panel Discussion with Q&A Session

SESSION XVI
Pulsed Field Ablation of VT
Moderator: Srinivas Dukkipati, MD
Digital Moderator: Francis Marchlinski, MD

The Promise of PFA for VT Ablation: Is it Really a Game Changer?
Elad Anter, MD

Prediction of Durable PFA Lesion Size in the Normal and Scarred Ventricular Myocardium
Hiroshi Nakagawa, MD, PhD

Updates: PFA and the Ventricular Substrate
Jacob Koruth, MD

Pulse Field Ultra-Low Temperature Cryoablation: Lesion Creation and Effect on Coronary Arteries in a Swine Model
Edward Gerstenfeld, MD

Prerecorded Case - Combined RF and PF for VT Ablation
Atul Verma, MD

Real Time Feedback During PFA in the Ventricle
Harikrishna Tandri, MD

Panel Discussion with Q&A Session